Tuesday, 14 December 2010

Priapism

Priapism is a potentially harmful and painful condition brought about as a result of having an erection for an extended period of time (over four hours). The condition usually comes about despite the lack of physical or mental stimulation and is a medical emergency.

Priapism can arrise via various different neurological and vascular factors. Men with spinal injuries have been known to suffer from priapism. 35% of male sufferers of sickle-cell disease have experienced it (click). Intra-cavernous injections for the treatment of erectile dysfunction can also cause priapism as can some anti depressants.

An extended erection can cause damage to the tissue and blood vessels within the penis. This can result in erectile dysfunction, impotence or in extreme cases, gangrene. Immediate hospital treatment should be sought if you experience prispism, as there are various options for helping to reverse the priapic state. If reversal is not achieved quickly, corporal fibrosis can occur, which can result in peyronie's disease like symptoms.

In men damaged as a result of priapism there is however some hope. In this study, two men who suffered from priapism of greater than 48-hour duration benefited from a treatment also used to treat peyronie's disease, the PAV cocktail. The PAV cocktail consists of Pentoxifylline, L-arginine and Viagra, and through increasing nitric oxide production can have an antifibrotic effect.

The study notes that "At 1 year, both patients were found to have supple corpora without evidence of corporal fibrosis.". It's a shame there aren't more studies into this particular treatment regimen for priapism at this time, but it at least provides a long term treatment option, on top of the well understood emergency ones.

Sunday, 12 December 2010

Peyreton

Recently I saw a forum post from a man concerned that a herbal supplement called Peyreton, had not helped his condition at all. Unfortunately it's no surprise that it doesn't work, as this thread on the peyronie's forum attests.

On the Peyreton site, the 'Ingredient Details' are listed as:



None of these ingredients have ever been shown to be at all useful in any reliable, peer reviewed peyronie's disease study. It's as if the ingredients were randomly thrown together and I fail to see how they are at all useful in treating peyronie's disease. It has the hallmarks of a scam.

The Peyreton site also includes an 'Expected Results' area:



Unfortunely no oral treatment in existence can boast the ability to effectively cure peyronie's disease within a three month period. This claim is entirely without merit and gives men false hope.

The 'Research Studies' on the site are carried out by 'The Gordon's Herbal Research Center'. A quick google on that topic reveals this post. It appears that the ingredients for many of their miracle cures (for widly different conditions) are either identical or very similiar. The site even states concerns that thse supplements may even be dangerous to some individuals.

My advice would be to avoid Peyreton and any product under the Gordon's Herbal Research Center umbrella. Peyreton certainly will not help treat peyronie's disease. What it will do is waste your time, money and result in disappointment. It's a scam. Avoid.

Friday, 10 December 2010

Email - Penis Bend

Dear Peyronie's Disease UK,

I have just done a google search and came across your Peyronies site.
I noticed, completely out of the blue, a bend in my penis in September. It was a shock.
Since then have been to doc who referred me to Preston hospital, where the consultant said to leave it 6 months and then see him again.
He did say, somewhat casually, I might try vitamin E and Ibuprofen, but didn't say what kind of doses?
Good wishes, and trying to keep in good spirits.

A

--------------

Hi A,

My advice to you would be to try to get on pentoxifylline (aka trental). This is a drug that has shown at least some promise in the treatment of peyronie's disease. The consultants advice wasn't very useful in my opinion.

As pentoxifylline has shown to be useful in some men so I'd stick with that for 6 months to a year and then re-evaluate the situation. Perhaps the bend will improve somewhat over the period. In either case, if it is stable at not painful at a year to 18 months after injury and is still quite severe it may be worth trying to get surgery on the NHS.

Use of a VED or traction device may also be something you wish to explore. As a fellow sufferer, I undestand how difficult this condition can be to deal with. Keep your chin up. It might be worth your time to check out the peyronies disease forum. Talking through issues with those in similiar positions can often be helpful.

Regards,

Peyronie's Disease UK

Wednesday, 8 December 2010

Email - Peyronie's Disease Concern

Dear Peyronie's Disease UK,

I first discovered or heard about peyronie's disease around 2 months ago. I noticed a bend out of nowhere after a particularly stressful week and researched on the internet. For the first month I went into a state of shock and didn't do anything about it apart from worry as it seemed no one could help. I started taking VIT- E 400mg, Potaba (6 a day). MSM sulphur and using other herbal remedy's such as knotgrass which apparantly improves elasticity in tissues also using VIT- E oil, started quite regimented but of late have been very hap-hazard.

I found my urologist to be very friendly, he has put me forward for a MRI scan on the NHS. However I still feel very frustrated at the lack of any kind of schedule to stick to, it just seems there's a make it up as you go along approach. I'm aware your e-mail is there mainly for people to contribute rather than advice but i'm only 25 and just seem to be going round in circles.

Given my age, nature and stage of my condition assuming it could be peyronie's, what would you recommend? Looking back I have always suffered some kind of ED without ever really doing anything about it, would the PAV cocktail and VED be a good option? If so what kind of dosage would you recommend? Also whats the best dosage of VIT-E. Would you suggest taking VIT-C as well?

Would be a great relief to hear from you even if its just a message to repeat whats on your site. Its great to see someone like yourself taking positive action.

Best Regards,

C


-----


Hi C,

It is very hard to know how the condition will develop at this stage since you're only two months in. In some men the condition will remain stable, in others it will worsen, and in a lucky few it is thought to spontanesouly resolve. I would say that in six-ten months if your condition is the same as it is now, it's quite unlikely to worsen. I say this because urologists usually wait around a year before considering surgery. With the right treatment approach, you can hopefully stack the odds in your favour.

The PAV cocktail is used by Dr Levine and Dr Lue. Both world renowned in the field of peyronie's disease. The most effective part of the PAV cocktail is pentoxifylline. I posted a study which is perhaps the most promising peyronie's disease oral treatment study ever (not as though there is much competition for that title! - aside from the new COQ10 study). It's certainly not a miracle cure, and in some men no oral treatments will help, but the study suggests that pentoxifylline can help to stop progression of the condition in many men, and can improve the condition of some. It's a prescription medication (as is the Viagra part of the cocktail). The 'A' in PAV cocktail, L-arginine is available from health stores like Holland and Barrett and is very cheap.

I don't think Vitamin C will be of most use, so personally I wouldn't bother to take it. I'm not convinced that Vitamin E is very useful either, but it has been stacked with Pentoxifylline in some fibrosis studies, so perhaps it serves a purpose in that combination. A full spectrum vitamin E might be a better option than one from a local chemist. This kind of thing.

I wouldn't dissuade you from going the VED route. A multi pronged approach can pay dividends. Traction has also been demonstrated to reduce curvature somewhat in a study from a year or two back. There's not really a right way or wrong way to approach treatment, but while the condition is still active is makes sense to channel your efforts in a positive fashion.

Thanks,

Peyronie's Disease UK

Saturday, 4 December 2010

Email - Spontaneous Recovery

Dear Peyronie's Disease UK,

Thank you for your blog site. It's very helpful in its clear, concise but comprehensive nature. I'm a relatively new, young sufferer (29) and not dealing very well with the psychological implications. Do you think spontaneous recovery is valid? I don't believe your site directly addresses the issue, and statics on the Internet vary significantly with no real detail or case examples. Keep in mind that holding on to the idea of spontaneous recovery is very important to those early sufferers for whom hope is fragile.

Thank you, again, for your site, you are greatly appreciated by your readers.

M
-----

Hi M,

You've reminded me to write one or two posts about the psychological angle in future. I have heard of a few anecdotal reports of spontaneous recovery online. I'd prefer the term spontaneous improvement though (rather than recovery), as it seems more realistic than complete recovery. In taking a proactive approach towards treatment (Pentoxifylline, VED, Traction etc) I feel that it's possible for many men to make good improvements. It isn't an overnight answer though, a long term view is required. Once the condition is stable, there are options such as surgery, but if conservative treatments are somewhat successful, or improvements occur on their own, surgery may not be required.

Thanks,

Peyronie's Disease UK

Sunday, 14 November 2010

Vacuum Erection Devices: Role in the Treatment of Erectile Dysfunction and Early Penile Rehabilitation


This study is a good example of the role that vacuum therapy has in improving erection quality and preventing the build up of penile scarring, specifically in those who have received treatment for prostate cancer. It is becoming acknowledged that there is a link between radical prostatectomies and peyronie's disease. This potential side effect of prostate cancer surgery can often be avoided, but rather worryingly does not appear to be widely known, or is not properly conveyed to, or understood by patients.

A great indepth article is featured on the cure peyronie's website detailing this issue. If you know anyone considering prostate surgery, please ensure that they enquire into this, and avoid the burden of peyronie's disease.

Topical Ibuprofen

I read a forum post recently concerning a peyronie's disease sufferer who ended up with terrible stomach problems as a result of taking too much Ibuprofen over a prolonged period of time. It's of course very unfortunate for a person to end up with with additional health concerns as a result of trying to deal with an ongoing one. No matter when health issue you have, it's of utmost importance to realise that your body and health exist beyond that one problem.

It's common for peyronie's disease sufferers to take ibuprofen and other NSAIDS (non-steroidal anti-inflammatory drugs) in the early days of the condition, where pain can be a significant problem. The extent to which it is helpful is hard to ascertain, but of course constant pain is difficult to live with, and as such taking something to help diminish it is a logical step to take.

Pain is not always entirely predictable though. Some men with peyronie's disease never suffer from pain, others do for many months and beyond. While Ibuprofen is relatively safe in the short term, a person taking it for month after month is bound to eventually encounter some side effects. Worse still if the approach does not provide the relief they had hoped from this or other treatments, the individual may increase the dose to unsafe levels. This is certainly a mistake.

In my view a MUCH more sensible approach is to apply topical ibuprofen, as opposed to the oral version. There are no peyronie's disease specific studies relating to this, but studies I've read on sporting injuries suggest that not only is topically applied ibuprofen useful in helping with pain, but much less of it circulates through your system as a result of its use. The peyronie's pain issue relates to the penis, so it's surely sound logic to avoid involving the rest of the body to as much a degree as possible, and side step many negative side effects in the process.

On top of this, topical Ibuprofen is fairly cheap and available at major supermarkets. You can even buy liquid capsules. Breaking these open and using them topically can be handy as it helps ensure that you use the same dose on every application.

Further reading:
Oral vs Topical Ibuprofen Knee Pain Study: http://www.ncbi.nlm.nih.gov/pubmed/20859315 (2010)

Sunday, 24 October 2010

Treatments

Below is an overview of a typical approach to treating peyronie's disease.

Oral Treatments - Front Line Treatments

Pentoxifylline - A prescription medication. Pentoxifylline has been offered to peyronie's patients since 2002 by renowned peyronie's disease expert Dr Tom Lue (and others). It's a conservative treatment and only moderately effective, but studies exist to back it up.

Second Line Treatments

These treatments either have positive studies directly relating to peyronie's disease treatment (COQ10, ALC) or in theory may be useful in combination with front line treatments.

Coenzyme Q10 - A very recent study suggesting that Coenzyme Q10 may have a meaningful place in peyronie's disease oral therapy. Time will tell whether or not this is the case.

Acetyl L Carnitine - The linked text directs you to a positive acetyl-l-carnitine study from a few years back. Acetyl L Carnitine isn't exactly heavily researched for the treatment of peyronie's disease, but it can't hurt to try it.

PDE5 inhibitors inhibitors (Viagra, Cialis, Levitra --> Comparsion) and L-arginine - Pentoxifylline, L-Arginine and Viagra is sometimes known as the PAV cocktail. It has been prescribed by some of the top urologists in the states as a combination aiming to help combat peyronie's disease.

Other Treatments

These treatments I'd describe as 'general', in the sense that they have not been shown to help with peyronie's disease (often no studies have involved their use), but in theory they have help reduce inflammation, scarring and so on in other conditions. Hence, they may be of use.

Pycnogenol - When combined with L-arginine pycnogenol is known to promote and improve the quality of erections. It it sometimes known as Prelox. Multiple studies support its effectiveness in treating mild to moderate erectile dysfunction.

All of the following also have anti inflammatory and/or antifibrotic qualities: Taurine, Vitamin D, Curcumin, Resveratrol.

Note: It is recommended that oral treatment regimens are combined with a mechanical treatments such as Traction or Vacuum Therapy. Typically traction or vacuum therapy is tried for 6 months or so. If the improvement is not satisfactory to the patient, he may consider that it is worthwhile sticking with these treatments, or undergoing surgery. Surgery only takes place when the condition is stable (typically a year or so after onset). Not all cases of peyronie's disease follow typical timescales. A urologist will advise you on which path to take. Helpful communities such as the peyronie's forum, may also provide comfort and assistance to sufferers.

Wednesday, 20 October 2010

Bent Penis

If you've found your way here, possibly by searching for the term bent penis, it's likely that you have concerns about the shape of your penis and wish to see what treatment options are available. In short, if you have a bent penis the condition is either caused by congenital curvature or peyronie's disease.

With congenital curvature the penis has always been curved and has not changed in shape in recent months or years. Congenital literally means 'existing at birth'. Often the curvature is slight and of no consequence, but sometimes it is more pronounced creating a feeling of insecurity and in more severe cases making sexual intercourse difficult.

Peyronie's disease, an inflammatory condition, differs in that it develops over time and as such it can be very noticable and psychologically troubling. Sometimes peyronie's disease is caused by a sexual injury, but often there is no noticable event. PD can be painful, but isn't always, and curvature and nodules can develop suddenly or over a period of time. The curvature is caused by plaque (scarring) which reduces elasticity within the penis. It can also be widespread rather than localised resulting in a shortening of the penis rather than noticable 'bent penis' appearance.

For peyronie's disease studies indiciate that pentoxifylline is a somewat useful oral treatments. There are also various studies demonstrating that traction devices can be used to significantly reduce curvature. As can ved therapy. There are surgical options too, though it certainly makes sense to try conservative options first.

For congenital curvature I would suggest traction as way of stretching the short side of the penis. Traction devices have been shown to be able to stretch tissue within the penis, increasing length in the process. Where there is curvature, the curve exists due to that part of the penis being shorter. As such this is the tissue that would be stretched by such a device [Product Page].

More traction device info:

Thursday, 14 October 2010

Vitamin D

I've blogged about many supplements on this blog before, so it seems like to good idea to make sure that Vitamin D is covered too. I don't wish to portray Vitamin D as a peyronie's disease specific treatment, because it isn't, but in terms of general health it deserves to be highlighted. Peyronie's disease often brings about an increased awareness and responsibility for ones general health and this is an extension of that.

Over the past few years, the momentun behind vitamin D, better described as a hormone rather than a vitamin, has been growing steadily. A great many of us are deficient in the vitamin, with diets lacking in sufficient Vitamin D, and exposure to sunlight lacking in the colder months. In some countries common foods are often fortified, but I've noticed that Vitamin D fortification isn't anywhere near as common here. Vitamin D levels in individuals can vary significantly. 5000 Units per day isn't a particulalry outlandish amount to take and aiming for a 25-hydroxy vitamin level of 60-70 ng/ml is thought to be about right (recommended by the popular heartscan blog).

Vitamin D is known to influence over 200 genes associated with common disease and ailments and those with adequate levels of it have significantly reduced incidences of several cancers. A deficiency of vitamin D can promote inflammation, which is certainly a concern for those of us with peyronie's disease.

Vitamin D tests are more common nowadays as deficiency in the vitamin is become recognised in many quearters. Take a look at this recent news item from the BBC News website concerning low vitamin D levels throughout Scotland, and this article about deficiencies amongst certain racial groups. The idea that Vitamin D only relates to bone health is very outdated and unhelpful.

Wednesday, 13 October 2010

Coenzyme Q10

In August, I posted about a positive Coenzyme Q10 study relating to peyronie's disease. As with all things peyronie's disease related, figuring out the benefits of a treatment tends to be something that takes months rather than days or weeks. As such I can't personally give a recommendation of whether it's a worth treatment, other than suggesting that in trying it, you don't have much to lose, and there is at least potential for gain.

I ordered Healthy Origins COQ10 Kaneka Gels from US company iherb. I tend to order from there because they're professional and offer good value (even after the rather unfair UK customs charges are taken into account).

I'm taking one 300mg pill a day and will continue to do so for six months, at which time I will consider whether or not it's been useful. Bare in mind that I've had peyronie's disease for quite some time, so even if this is useful, I personally may not experience the positive effects of it. If anything, the supplement side of my regimen is to make sure that there's minimal chance of negative changes, while I engage in other treatments (traction, vacuum therapy etc).

A word to the wise. There two available forms of CoQ10, Ubiquinone and Ubiquinol. Your body has to break down Ubiquinone into Ubiquinol in order to use it. When you're young this is easy, but as you get older (40-50+) it becomes more difficult. As such for young people thinking of adopting a CoQ10 peyronie's disease strategy, should probably use Ubiquinone (it's cheaper too) and for those aged 40+ buy a Ubiquinol form of CoQ10.

CoQ10 Study PDF here.

VacADS

There's not exactly a miriad of options on the mechanical side of peyronie's disease treatments (vacuum pumps, traction devices) so aside from covering the basics and protocols used (ved protocol) the conversation usually ends there.

There are variations on a theme though, and the VacADS system is one that I recently tried and which was a positive enough experience to get me to write about it here. The device doesn't use the traditional noose method of fastsize and co. Instead a plastic helmet is placed on the head of the penis, and the device holds in place due to vacuum. It's more comfortable than you'd think and I tend to wear it for around 2 hours then remove it. I only place a light weight on the device, as I feel that I always need to adopt a long term strategy and accept that this isn't the case of waking up tomorrow and everything being back to normal. Also, fear of injury plays a part in such decisions.

The ADS part of VacADS stands for all day stretch. I'm not sure how someone could stretch all day long using this device though, as I imagine that they would experience a degree of fluid buildup due to the prolonged vacuum.

I still use a vacuum pump. I had a period of time where I developed some blood spots, which was frustrating for me, as I wasn't pumping any harder than usual. The supplements and medications that I take do thin my blood slightly though. Everything is a delicate balance and it's important to try to listen to your body and take a steady and sure approach to peyronie's disease treatments. I have considered alternating between traction and vacuum therapy of alternate days. This isn't a protocol that I've seen put forward and I'm not sure how wise it is to move onto the road less travelled. I do feel that there is evidence both strategies have merits though, which is the logic behind my thinking.

Each device has it's drawbacks and it's down to the individual to find out what works best for them. It certainly makes sense to go down the physical/mechanical option route though, as a combined approach of that and oral treatments is beneficial both physically and psychologically in my view. If you have any experiences to share of using either traction of VED (vacuum erectile device) therapy, feel free to post a comment.

Thursday, 2 September 2010

Bristol Urology

I don't highlight many urologists on the site, but I did recently see positive comments relating to the treatment of peyronie's disease at Bristol Urology. Apparently they readily prescribe pentoxifylline to peyronie's disease patience. This might not sound like something of note, but many urologists still don't prescribe it, despite the positive study we're seen and thumbs up from previous top urologists.

According to the site, for NHS patients, "if you live in North Somerset or South Gloucestershire, your GP can refer you to the BUA under the innovative 'GP Care' urology diagnostic scheme." The details of the scheme are on this page. The appointment waiting times under this scheme seem to be reasonably short and the details of what you can expect during the initial appointment are set on the page. I assume that those outside of the area can get referred to Bristol Urology through the NHS too, though it might differ slightly from the GP Care scheme. Apparently Consultant Urologist Dr Tim Whittlestone is a good person to talk to about your peyronie's disease concerns.

If any of you are past of present patients of Bristol Urology feel free to leave a comment detailing your experiences.

Thursday, 26 August 2010

Vacuum Erection Device Protocol Spreadsheet

This post contains a handy spreadsheet to enable you to follow the 26 week VED therapy protocol mentioned previously on the blog (link: vacuum therapy protocol).

There's plenty of anecdotal evidence that using the VED can help men reduce penile curvature and/or enhance penile health in men with peyronie's disease. This is further backed up by a St Peter's Hospital study carried out recently (link: vacuum erection device study) which demonstrates that daily use of a medical grade pump really can reduce curvature of the penis somewhat in many men.

Despite this information, of course improvement is a gradual process. As a result many men become dishearted after only a short time and do not give the process a fair chance. The spreadsheet as an attempt to try to help men stick to a plan and monitor their progress over time. As with all approaches to treating peyronie's disease, this isn't a miracle cure and it won't work for all men. From both a physical and mental wellbeing perspective though, it's something that I'd recommend.

Download the spreadsheet HERE. (left click)

Thanks very much to Mike from the peyronie's forum for creating the spreadsheet and allowing it to be used here.

Monday, 14 June 2010

Regenerative Medicine

The peyronie's disease picture in 2010 isn't entirely bleak. Oral treatments such as pentoxifylline and mechanical methods like vacuum and traction therapy are 'finally' gaining an increased level of acceptance amongst urologists. Various positive studies on these treatments have also been published and are featured on the site. Actual peyronie's disease specific breakthroughs, though, are still sadly lacking. Aside from Xiaflex, legitimate future treatments are nowhere to be seen. Thankfully medical advances are happening in other areas which may eventually help sufferers of this condition.

Regenerative medicine may sound rather otherworldly to most people, but positive advances are being made in this field at a furious pace. The 'Wake Forest Institute for Regenerative Medicine' research institute, based in North Carolina, US, have engineered various cell and tissue types, and last year reconstructed penile tissue.

The process of regenerating the corpora cavernosa involves harvesting smooth muscle, multiplying the cells in a laboratory, implanting a 3D scaffold within the patient and then injecting the cells into that scaffold. In the rabbit model the whole process took about a month and resulted in a fully functional penis. In theory the rabbit model shouldn't differ all that much from a human one. The cells would be the patients own too and so shouldn't be rejected (no need for immunosuppressive drugs). This technology is in fact already used in humans. Functional human bladders have been regenerated and implanted for quite some time (source).

In the BBC News article, Professor Anthony Atala, the director of the institute, goes on to state that this technology may eventually be able to aid patients in need of penile reconstruction due to reasons of "congenital abnormalities, penile cancer, traumatic injury and some cases of erectile dysfunction". While he does not mention peyronie's disease by name his description covers aspects of the condition. It's worth pointing out that he was previously a urologist and as such likely has a good knowledge of peyronie's disease and recognises that there is a potential application of the technology to this area.

I'll write a follow up post when there is anything of note to add.

Monday, 31 May 2010

Pycnogenol + L-Arginine ( Prelox )

I posted briefly some time ago about how Pycnogenol and L-Arginine in combination has been demonstrated to be useful in the treatment of moderate erectile dysfunction. A new UK study came out recently which supports this view. (Other Prelox studies [1] [2]).

Men with peyronie's disease often suffer from varying degrees of ED and as such for those with mild to moderate erectile dysfunction, this could be an over the counter option that they wish to explore instead of prescription route of Viagra, Cialis and Levitra. The study shows an increase in erection strength and plasma testosterone levels. The prelox treatment appears to be as effective (if not more so) the longer the therapy is used.

Patients of Dr Levine is the US have been known to take the PAV cocktail or a variation of it for a period of months (Pentoxifylline, L-Arginine and Viagra). Since L-arginine is already being taken, I wonder what impact adding Pycnogenol to the mix would be, if anything? There certainly appears to be a level of synergy between Pycnogenol and L-Arginine.

Tuesday, 18 May 2010

Vacuum Erection Device (VED) Study

Below is a link to the new vacuum erectile device (VED) study that I mentioned in the previous post.

DOWNLOAD (212KB)


The use of medical grade vacuum pumps has been a part of the peyronie's disease community for years now. Despite this fact, and many positive anecdotal reports, urologist in general have not embraced the VED as a viable treatment option.

This study, the first I have seen in relation to vacuum devices, goes some way to showing that it may well be a useful treatment option for those sufferers from peyronie's disease. The results are far from miraculous, and the sample is small, but curvature did improve in many patients to the point where surgery was not required. This is certainly a positive development in the lives of those men. The fact that pain improved too is a very promising finding, because both short (weeks to months) and in a minority cases very long term pain can, both physically and mentally, be a very difficult aspect of PD to deal with.

Let's hope that there are further VED studies undertaken in future, and that these too have positive outcomes. Perhaps a combined studies (involving Vacuum AND traction) or a combination of vacuum device and oral treatments should be carried out. Pentoxifylline for instance can sometimes soften scarring and calcified areas. This VED study write-up suggests that on soft scars VED therapy results may be more pronounced, therefore, it does start to make the case for combined therapy studies.

Friday, 14 May 2010

The role of vacuum pump therapy in Peyronie's disease


This new study is somewhat positive. It confirms what many have already known/suspected for quite some time: That VED Therapy can be useful in combating peyronie's disease. Like all peyronie's disease treatments out there, there is no magic bullet, but it's always pleasing to get confirmation that a treatment is useful, and that you're on the right track. In the peyronie's disease community many men have been saying for years now that VED useage improved their situation and it's good to see that echoed in this study.

From the study we see that a relatively short course of VED therapy can be useful to men suffering from peyronie's disease. In the best case scenario can improve the condition to the point where surgery may not be needed. For some men in the study VED therapy meant the difference between requiring surgery and not. For others, it helped to increase their penis size pre-surgery, which again is certainly a positive occurence.

It's of note that for three men in the study their condition worsened. I feel it would be alarmist to state that VED caused this, when it seems more likely that the treatment simply did not manage to reverse damage already occuring in an active stage of the disease. In many cases it takes 12-18 months for peyronie's disease to reach an end point (sometimes beyond that). It's even possible that their situation would've been worse still if they had not used VED, so in a sense even they may have seen an improvement. Of course, it's a very individual condition, so to state absolutes either way is never wise.

It would be of interest to gather further information about the specific protocol used in this study, as a way of contributing to the knowledge already out there. Many men currently use the Chris Spivey protocol. Also, in combining VED therapy with oral treatments, I would think that the chances of a positive outcome would rise further still. Perhaps the men above were taking oral treatments at the same time. At present I only have the study info stated here. I'll try to find out more.

Wednesday, 12 May 2010

Peyronie's Disease Research

To the Editor: Re. Peyronie’s Disease information found at: www.Peyronies-disease.co.uk

Dear sir,

I found your website whilst looking for further information on Peyronie’s disease as part of a research study we are conducting to better understand the experiences, problems and issues faced on a daily basis by diagnosed Peyronie’s sufferers.

This research study will take the form of a 60-minute telephone interview with Peyronie’s patients who are willing to discuss the problems and issues faced since a diagnosis was made.

Eligible participants who go on to complete the interview will be offered £80 as a thank you for helping on this research. I would also like to stress that all information provided by participants in this research is treated in the strictest confidence, including names of participating individuals in accordance with the Data Protection Act. The research will be conducted under the Code of Conduct of the Market Research Society.

I would be grateful if you would post this information to any Peyronie’s patients who might be interested in helping out with this research. To help I have attached a flyer containing the full contact information for anyone interested in helping us with this research.

Many thanks in advance,

Kind regards,

Martin Evans

Direct Line: +44 (0)203 1300 640
Switchboard: +44 (0)203 1300 630
Fax Number: +44 (0)208 7882 042

martin.evans@healthcarelandscape.com